Enhanced global surveillance systems, including expanded genomic sequencing and early-warning networks, have contained recent outbreaks such as the 2026 Bundibugyo Ebola PHEIC in the DRC and Uganda to regional levels without sustained international human-to-human transmission. No novel pathogen has met WHO pandemic criteria through mid-2026, with respiratory viruses like influenza and circulating coronaviruses showing limited escalation potential per CDC and WHO monitoring. Post-COVID improvements in public health infrastructure and rapid response protocols further lower near-term risks, aligning with historical annual pandemic probabilities around 2–3% that make a new event before 2028 statistically unlikely under current conditions.